Asunto(s)
Queratosis/diagnóstico , Seudoxantoma Elástico/diagnóstico , Ombligo/patología , Antiinflamatorios/administración & dosificación , Clobetasol/administración & dosificación , Femenino , Antagonistas de los Receptores Histamínicos/administración & dosificación , Humanos , Queratosis/complicaciones , Queratosis/tratamiento farmacológico , Persona de Mediana Edad , Seudoxantoma Elástico/complicaciones , Seudoxantoma Elástico/tratamiento farmacológicoAsunto(s)
Queratosis/complicaciones , Queratosis/diagnóstico , Penfigoide Ampolloso/complicaciones , Penfigoide Ampolloso/diagnóstico , Administración Oral , Adulto , Femenino , Humanos , Queratosis/tratamiento farmacológico , Penfigoide Ampolloso/tratamiento farmacológico , Esteroides/administración & dosificaciónRESUMEN
Acrokeratosis paraneoplastica of Bazex is rare condition, characterized with scaly hyperkeratotic psoriasiform plaques on acral parts of body (helices, nose, and malar and acral surfaces), and in later stages propagation to the limbs and trunk.This syndrome is distinct marker for different neoplastic conditions, predominantly squamous cell carcinoma of the upper aerodigestive tract with possible cervical lymph node metastases.In this paper we present 56 years old male patient, with hyperkeratotic plaques on the skin of his palms, soles, ear lobes and apex of the nose. Detailed examination found tumorous swelling on the left side of his neck. Histopathologic examination revealed solid anaplastic metastatic tumor. Patient died before primary tumor could be found. Bazex syndrome can appear before the diagnosis of internal malignancies, and thus is important for dermatologists to recognize it in favor of early diagnosis of specific malignant process.
Asunto(s)
Queratosis/diagnóstico , Síndromes Paraneoplásicos/diagnóstico , Acrodermatitis/complicaciones , Acrodermatitis/diagnóstico , Resultado Fatal , Humanos , Queratosis/complicaciones , Masculino , Persona de Mediana Edad , Síndromes Paraneoplásicos/complicacionesRESUMEN
The ectodermal dysplasias are a heterogeneous group of disorders with primary defect in hair, teeth, nail and sweat gland function. Numerous types have been described and several classifications exist. Here, we present a patient with ectodermal dysplasia with alopecia, dysplastic nails, hypohidrosis, sensorineural deafness, palmoplantar keratoderma, abnormal teeth and dry skin. To our knowledge, combination of all these features in ectodermal dysplasia has not been reported in the past. The etiology is unknown, but consanguinity of parents points to an autosomal recessive inheritance.
Asunto(s)
Displasia Ectodérmica/complicaciones , Adulto , Alopecia/complicaciones , Sordera/complicaciones , Femenino , Humanos , Hipohidrosis/complicaciones , Queratosis/complicaciones , Uñas Malformadas/complicaciones , Anomalías Dentarias/complicacionesAsunto(s)
Queratosis/patología , Nevo/patología , Pezones/patología , Adulto , Enfermedades de la Mama/complicaciones , Enfermedades de la Mama/patología , Femenino , Humanos , Queratosis/complicaciones , Neoplasias Hormono-Dependientes/complicaciones , Neoplasias Hormono-Dependientes/patología , Nevo/complicacionesAsunto(s)
Queratosis/terapia , Lesiones Precancerosas/terapia , Carcinoma de Células Escamosas/tratamiento farmacológico , Carcinoma de Células Escamosas/etiología , Carcinoma de Células Escamosas/terapia , Legrado/métodos , Humanos , Queratosis/complicaciones , Queratosis/tratamiento farmacológico , Lesiones Precancerosas/tratamiento farmacológico , Lesiones Precancerosas/etiologíaRESUMEN
Two cases of borderline-tuberculoid leprosy which developed keratosis spinulosa over the anaesthetic areas alone during type I lepra reactions are described. Both patients only developed spiny papules during the period of reaction and subsided with control of the reaction. The probable mechanism of this peculiar phenomenon might be due to the generation of epidermal growth factors by local T cell activation during the type I lepra reaction.
Asunto(s)
Lepra Dimorfa/patología , Lepra Tuberculoide/patología , Adulto , Humanos , Queratosis/complicaciones , Queratosis/patología , Lepra Dimorfa/complicaciones , Lepra Tuberculoide/complicaciones , Masculino , Piel/patologíaRESUMEN
Three hundred and sixty six in-patients in a leprosy hospital were examined for other dermatological conditions. Eighty eight of them displayed ichthyosiform changes. A peculiar condition of a verrucous hyperkeratotic growth on the anterior aspect of ankle, not described previously, was observed in four patients. It was noted that 11 out of 12 patients with scabies did not have the classical lesions in web spaces of the hands.
Asunto(s)
Lepra/complicaciones , Enfermedades de la Piel/complicaciones , Clofazimina/efectos adversos , Erupciones por Medicamentos/complicaciones , Erupciones por Medicamentos/etiología , Femenino , Humanos , Pacientes Internos , Queratosis/complicaciones , Masculino , Trastornos de la Pigmentación/inducido químicamente , Trastornos de la Pigmentación/complicaciones , Escabiosis/complicacionesRESUMEN
Morphological and histopathological observations made over 4 years of 10 patients with porokeratosis are described. Absence of familial involvement was notable. Association of porokeratosis with tinea cruris, leprosy and epithelioma was seen, and their possible correlation is discussed.